Microfluidics LabChip Platform for Vaccines & Biologics

 

LabChip® GXII Technology for Vaccines and Biologics “10X Increase in Yield possible due to high throughput expression monitoring.” Dow/Pfenex Subunit Vaccine In the field of Vaccines and Biologics, the LabChip GXII has been widely adopted across the Discovery and Development pipeline by a large number of pharmaceutical and vaccine developers to improve their analytical capabilities for protein therapeutics and vaccines.   The LabChip performs rapid quantitative assessments of size, purity and titer, directly from 96- and 384-well plates and is applicable to vaccine strain development, protein subunit expression optimization, vaccine formulation development & stability, and QC methods development & QA.  Protein Analysis Recombinant Subunit Expression Optimization and Tracking Subunit Purification Tracking Formulation Development – Excipient Assessment, Purity, Stability, Modification, Aggregation, Degradation Product Quality Assessment – Purity, Stability, Modification, Aggregation, Degradation Virus Like Particle (VLP) Characterization Glycan Analysis Identification of main glycans Analysis is 60 seconds per sample Less than 6 hours from prep to final analysis for 96 samples Reagents provided in a convenient 96-well plate format   Click here for more information on the LabChip GX system for vaccines & biologics. Customer Quotes about the LabChip GXII platform for vaccines and biologics:“Screen the performance of pharmaceutical excipients. The LabChip GXII is used to monitor the chemical and physical stability of the antigen within complex matrix of excipients, before and after stress.”  Scientist, R&D Formulation Development, Belgium “LabChip enables us to perform experiments in an afternoon that would have required a month.” Biogen-Idec, COG 2009 “Finally, the process that we have described reduces both experimentation cost and time while increasing throughput, making possible what–if experiments that, up to now, had been either prohibitively expensive or too complex to perform. This process results in better solutions, decreased development time and increased productivity.”   Vertex, Anal. Biochem. 2006:351 p122 “Expression screen by magnetic bead purification and Caliper LabChip gives objective and quantifiable results.”   Boehringer Ingelheim, Global Protein Summit, London, 2006

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